significant changes in the activity of l-glutamic acid decarboxylase of mouse hypothalamus after peripheral injection of cholecystokinin-8 and caerulein

نویسندگان

راضیه یزدان پرست

razieh yazdanparast دردی قوجق

durdi qujeq

چکیده

the activity of one of the metabolizing enzymes of - aminobutyric acid, (gaba), was determined in mouse hypothalamus after peripheral injections of cholecystokinin-8 (cck-8) and caerulein (cln). the activity of this rate-limiting enzyme, l-glutamic acid decarboxylase, (gad), did not change thirty minutes after peripheral injections of either cck-8 or cln in doses of 50g/kg body weight. however, the activity of gad started to increase 24 hours after injection and continued to increase by 15 to 17%, five days after injections. based on the in vitro models, it has been shown that there are no direct interactions between cck-8 and cln and the enzyme gad. these data probably support indirect but specific interactions between cck-8, cln and the enzyme gad.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Significant Changes in the Activity of L-Glutamic Acid Decarboxylase of Mouse Hypothalamus After Peripheral Injection of Cholecystokinin-8 and Caerulein

The activity of one of the metabolizing enzymes of - aminobutyric acid, (GABA), was determined in mouse hypothalamus after peripheral injections of cholecystokinin-8 (CCK-8) and caerulein (CLN). The activity of this rate-limiting enzyme, L-glutamic acid decarboxylase, (GAD), did not change thirty minutes after peripheral injections of either CCK-8 or CLN in doses of 50g/kg body weight. Howeve...

متن کامل

Significant Changes in the Activity of L-glutamic Acid Decarboxylase of Mouse Hypothalamus after Peripheral Injection of Cholecystokinin-8 and Caerulein

The activity of one of the metabolizing enzymes of aminobutyric acid, (GABA), was determined in mouse hypothalamus after peripheral injections of cholecystokinin-8 (CCK-8) and caerulein (CLN). The activity of this rate-limiting enzyme, L-glutamic acid decarboxylase, (GAD), did not change thirty minutes after peripheral injections of either CCK-8 or CLN in doses of 50g/kg body weight. However,...

متن کامل

SIGNIFICANT CHANGES IN THE ACTIVITY OF GABATRANSAMINASE AND SUCCINATE SEMIALDEHYDE DEHYDROGENASE OF MOUSE HYPOTHALAMUS FOLLOWING PERIPHERAL INJECTION OF CHOLECYSTOKININ-8 AND/OR CAERULEIN

The activities of 4-aminobutyric-2-oxoglutaric acid transaminase (GABA-T) and succinate semialdehyde dehydrogenase (SSADH) were determined in mouse hypothalamus after peripheral injections of cholecystokinin-8 (CCK-X)and/or caerulein (CLN). GABA transaminase activity was measured utilizing endogenous succinate semialdellyde dehydrogenase to convert the product of GAB A-T, succinate semiald...

متن کامل

significant changes in the activity of gabatransaminase and succinate semialdehyde dehydrogenase of mouse hypothalamus following peripheral injection of cholecystokinin-8 and/or caerulein

the activities of 4-aminobutyric-2-oxoglutaric acid transaminase (gaba-t) and succinate semialdehyde dehydrogenase (ssadh) were determined in mouse hypothalamus after peripheral injections of cholecystokinin-8 (cck-x)and/or caerulein (cln). gaba transaminase activity was measured utilizing endogenous succinate semialdellyde dehydrogenase to convert the product of gab a-t, succinate semialdehyde...

متن کامل

comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.

heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...

15 صفحه اول

the analysis of the role of the speech acts theory in translating and dubbing hollywood films

از محوری ترین اثراتی که یک فیلم سینمایی ایجاد می کند دیالوگ هایی است که هنرپیش گان فیلم میگویند. به زعم یک فیلم ساز, یک شیوه متأثر نمودن مخاطب از اثر منظوره نیروی گفتارهای گوینده, مثل نیروی عاطفی, ترس آور, غم انگیز, هیجان انگیز و غیره, است. این مطالعه به بررسی این مسأله مبادرت کرده است که آیا نیروی فراگفتاری هنرپیش گان به مثابه ی اعمال گفتاری در پنج فیلم هالیوودی در نسخه های دوبله شده باز تولید...

15 صفحه اول

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian biomedical journal

جلد ۳، شماره ۱، صفحات ۴۷-۵۱

کلمات کلیدی
[ ' c a e r u l e i n ' , ' c h o l e c y s t o k i n i n ' , 8 , ' g a b a ' , ' l ' , ' g l u t a m i c a c i d d e c a r b o x y l a s e ' ]

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023